FurosemidePA study guide
Known brand names include Lasix and Furoscix.
A strong "water pill" that makes the kidneys pass more salt and water. It treats swelling from heart, liver, or kidney disease, fluid in the lungs, and high blood pressure.
Known brand names include Lasix and Furoscix.
A strong "water pill" that makes the kidneys pass more salt and water. It treats swelling from heart, liver, or kidney disease, fluid in the lungs, and high blood pressure.
Labeled use. Oral, alone or combined. Patients not controlled on thiazides usually will not be controlled on furosemide alone.
Sources: [1]
The usual choice for edema and volume overload, including acute pulmonary edema, and when kidney function is too low for thiazides to work. For uncomplicated hypertension, a thiazide is generally preferred because loop diuretics act briefly.
The label does not describe a narrow therapeutic index or direct dosing by measured blood levels of the drug.
Doses come from the FDA label. Study tool, not for clinical decisions.
No fixed renal dose table. Contraindicated in anuria; stop if azotemia and oliguria worsen in severe progressive kidney disease. Ototoxicity risk is higher with severe renal impairment, so avoid rapid injection and high doses.
None on the current label. The oral label opens with an unboxed warning that excess doses can cause profound loss of water and electrolytes.
No antidote. Overdose causes dehydration, low blood volume, hypotension, and electrolyte loss. Replace fluid and electrolytes and check electrolytes, CO2, and blood pressure often. Hemodialysis does not speed elimination.
Sources: [1]
No adequate human studies. Use only if benefit justifies risk, and monitor fetal growth because birth weights may run higher. Animal studies showed maternal deaths and abortions in rabbits.
Sources: [1]
Passes into breast milk, and strong diuresis may reduce milk supply. Use with caution.
Oral: 2 mg/kg to start; if needed, add 1 to 2 mg/kg after waiting at least 6 to 8 hours; doses above 6 mg/kg are not recommended. IV or IM: 1 mg/kg to start; premature infants should not exceed 1 mg/kg/day. Can cause nephrocalcinosis in premature infants and in children under 4 on long-term use, so monitor renal function.